Then the visitors called a useless timeout while they were trailing 42-10 with three minutes left in the game to preserve the clock, and Manning just shook his head.
But when San Francisco also took a timeout before an extra point attempt after scoring a touchdown with one minute left, Manning's dismay turned into a WTF.
Read his lips:
At least he can smile knowing he has the historic football to take home with him. Oops, about that spot on your mantle, Peyton.